Scientific Information

Organising Institutions

Birth and Culture – Nascita e Cultura

Nascita e Cultura is a non-profit association inspired by the values of scientific, deontological and bioethical culture in life sciences which aims to affirm, promote and enhance the global culture of the health of the mother, the fetus and the newborn, understood as the achievement of the highest degree of mental, physical and social well-being, according to the guidelines of the World Health Organization.

Congress Committees

Presidents
Virology
 
Immunology
Pediatrics
 
Epidemiology
Fetal Medicine
 

Scientific Programme

09:00-09:05

WELCOME

Yves Ville, France

09:05-09:20

Priorities for current research: Results of a European survey

Pamela Vallely, United Kingdom

09:20-09:35

Patients’ voice. Their priorities:

Anne Hélène Labissy, France

09:35-09:45

Discussion

09:45-10:15

BREAK AND POSTER VIEW

10:15-11:30

EPIDEMIOLOGY IN EUROPE

Chairs: Suzanne Smit, Belgium; Marianne Leruez, France

10:15-10:30

Overview

Suzanne Smit, Belgium

10:30-10:45

The high risk group

Marianne Leruez, France

10:45-10:50

Congenital CMV infection following maternal infection in the second and third trimester of pregnancy is associated with mild sequelae not predicted by prenatal imaging

Shlomo Lipitz, Israel

10:50-10:55

Survey of congenital cytomegalovirus in France : focus to fetal and newborn symptomatology in 2018 and 2019

Elodie Ribot, France

10:55-11:00

Antibody features and functions distinguish primary from latent CMV infection during pregnancy

Andrew Hederman, United States

11:00-11:05

Congenital cytomegalovirus awareness among pregnant women in a tertiary hospital in Barcelona, and knowledge of the infection among prenatal health care providers in Catalunya (Spain): an action towards prevention

Anna Gonce, Spain

11:05-11:10

Evolution of awarness and knowledge of congenital cytomegalovirus infection among health care providers in France between 2001 and 2018

Christelle Vauloup Fellous, France

11:10-11:30

Discussion

12:00-15:30

PREVENTION

Chairs: Chrissie Jones, United Kingdom; Arnauld Marchant, Belgium

12:00-12:15

PRIMARY PREVENTION

12:00-12:15

Overview

Chrissie JONES (UK)

12:15-13:45

SECONDARY PREVENTION

12:15-12:45

Debate:

HIIG work : the MFMN randomized trial of cytogam to prevent congenital cytomegalovirus infection was flawed Stuart Adler, United States HIIG do not work : Daniele Lilleri, Italy

12:45-13:00

How to optimize passive immunization for prevention of maternofetal CMV transmission: impact of virological inclusion criteria

Karl Oliver Kagan, Germany

13:00-13:15

Val-acyclovir to Prevent congenital CMV After Maternal Primary Infection early in Pregnancy

Jacob Amir, Israel

13:15-13:20

Fibroblast infection by cytomegalovirus has evolved a mechanism to escape neutralizing antibodies

Michael Mcvoy, United States

13:20-13:25

Trimeric artesunate TF27 shows strong anti-cytomegalovirus efficacy by oral administration in vivo and favorable drug interactions in vitro

Markus Wild, Germany

13:25-13:30

Treatment of women with a primary CMV infection in pregnancy with high-dose CMV hyperimmune globulin (cytotect) does not cause placental syndrome.

Stuart Adler, United States

13:30-13:45

Discussion

13:45-14:15

BREAK AND POSTER VIEW

14:15-15:15

TERTIARY PREVENTION (Fetal and Neonatal treatment)

14:15-14:30

Antiviral treatment in pregnancy

Marianne Leruez, France

14:30-14:45

Neonatal treatment (overview)

Ann Vossen, the Netherlands

14:45-14:50

Antiviral targeting strategies based on pharmacological inhibitors directed to the human cytomegalovirus-encoded protein kinase pUL97

Manfred Marschall, Germany

14:50-14:55

Impact of letermovir in an ex vivo first-trimester placenta model.

Elodie Ribot, France

14:55-15:15

Discussion

09:30-10:30

DIAGNOSTIC OF MATERNAL INFECTION

Chairs : Ann Vossen, the Netherlands; Tiziana Lazzarotto, Italy

09:30-09:35

Welcome to Day 2

09:35-09:50

Overview primary infection

Tiziana Lazzarotto, Italy

09:50-10:05

Overview Non-primary infection

Daniele Lilleri, Italy

10:05-10:30

Discussion

10:30-11:00

BREAK AND POSTER VIEW

11:00-11:45

DIAGNOSTIC OF FETAL INFECTION

Chairs : Catherine Donner, Belgium; Anna Gonce, Sweden

11:00-11:15

Overview

Yves Ville, France

11:15-11:20

Antibody response to primary cytomegalovirus infection during pregnancy

Shilpee Sharma, Belgium

11:20-11:25

Does T-cell mediated immune response to cytomegalovirus infection play a role in preventing intrauterine transmission? (cytric study)

María Soriano-Ramos, Spain

11:25-11:30

Cortical maturation assessed by magnetic resonance imaging in unaffected/mildly affected fetuses with cytomegalovirus infection.

Ameth Hawkins-Villarreal, Spain

11:30-11:35

RNA sequencing of amniotic fluid reveals activation of the innate immune response and differential expression of neurodevelopmental transcripts in midtrimester human fetuses with cytomegalovirus infection

Lisa Hui, Australia

11:35-11:40

Serial ultrasound assessment for identifying fetuses at risk of postnatal sequelae from cytomegalovirus infection: an Italian multicenter retrospective study

Sara Ornaghi, Italy

11:40-11:45

The performance of amniocentesis for the diagnosis of congenital cytomegalovirus infection at 17 weeks of amenorrhea is just as strong as when performed one month later

Valentine Faure Bardon, France

11:45-12:00

Discussion

12:00-12:30

VACCINE quo vadis

12:00-12:15

Overview

Arnauld Marchant, Belgium

12:15-12:20

A Messenger RNA (mRNA) Vaccine Against Cytomegalovirus (CMV) Infection: Phase 2 Interim Data

Lori Panther, United States

12:20-12:30

Discussion

12:30-13:15

BREAK AND POSTER VIEW

13:15-14:15

PEDIATRICS - PART 1

Chairs : Daniel Blazquez-Gamero, Spain; Ina Foulon, Belgium

13:15-13:30

Management of SNHL

Ina Foulon, Belgium

13:30-13:45

Implants: technique and outcome

Natacha Tessier, France

13:45-13:50

Eagle score. A multicentric cohort study about hearing loss in congenital cytomegalovirus infection.

Serena Villaverde, Spain

13:50-13:55

Cochleovestibular involvement in human fetuses with congenital CMV infection

Liliana Gabrielli, Italy

13:55-14:15

Discussion

14:15-14:45

BREAK AND POSTER VIEW

14:45-15:45

PEDIATRICS – PART II

ChaiChairs: Daniel Blazquez-Gamero, Spain, Ina Foulon, Belgium

14:45-15:00

Pediatric burden of non-primary infections

Vanna Papaevangelou, Greece

15:00-15:05

Kinetics of salivary and blood viral loads in a cohort of children with congenital CMV infection

Jacques Fourgeaud, France

15:05-15:10

Cranial ultrasound and MRI : do both matter in the diagnostic work-up of children with congenital CMV?

Annelies Keymeulen, Belgium

15:10-15:15

Evaluation of the SIMPLEXA™ congenital CMV direct assay for newborn cytomegalovirus testing using saliva and urine samples

Tiziana Lazzarotto, Italy

15:15-15:30

Discussion and closing remarks

Accreditations

CVS Ethical Medtech

The EMT20368-European Congenital Cytomegalovirus Initiative starting on 23-04-2020 in Paris, France is compliant with the MedTech Europe Code of Ethical Business.

For more information visit: www.ethicalmedtech.eu